August 8, 2013
What's in it for you as a scientist – you have many demands on your time.
You want to do science and you find yourself spending 90% of your time putting out fires and explaining to others what you already know. And chasing the almighty Dollar, Euro, Yen or Rupee with grants, grant, grants or potential partner presentations. You know you are good at the science, but with so little time to do actual science, you really need powerful tools that allow you to quickly analyze salient trends. You need to see what’s happening quickly, so you have more time to think, reflect, and propose newer, better, richer hypotheses and experiments.
Luckily for you there is this powerful, collaborative CDD Vault that is a delight to use in numerous ways that are even sometimes hard to put your finger on it. The basics are trivially easy to master and the more advanced capabilities go deep in multiple directions of interest (SAR, IC50, averaging, normalization, heatmaps, scatterplots). And it is trivial to import or export results to and from Excel or specialized applications. Now with the CDD Vault Enterprise and templates, that can even be all automated.
The more you and your colleagues use it, the more you like it, the more you login to view and navigate and securely share trends.
Relative to the overhead that you thought was required to use sophisticated technologies, you were pleasantly surprised to see your group was up, running and seeing immediate benefits even within a month of starting with the CDD Vault. At first, you had a healthy skepticism, as you would with anything new, but now you are won over. Obviously there is something different with this type of modern web-based technology. You are working with dedicated folks at CDD that clearly have your back (CDD internally calls them "team awesome". They support your group as if you were a huge multi-million dollar paying client. Even though you are obviously not their biggest customer (unless you are) – you still feel like it. If you have time to reflect on it, this is surprising, how can this be so, and yet it is.
The CDD platform is delightful to use for biologists and chemists, experts and newbies. You’d always thought these types of scientific informatics technologies had to be painful, clunky applications just for experts. CDD was created with great empathy for the mainstream scientist just trying to do his or her job. Biologists easily customize protocols, do QC analysis of each run, and generate reports. You are amazed such an intuitive software correctly handles IC50, MIC99, Ki, ED50, pIC50, TD50, % inhibition raw data, time-dependent measurements, averages, normalizations, comments, plates/well trends, Z/Z’, absolute stereochemistry, relative stereochemistry, SAR, and more. Chemists and biologists combine complementary impressions on the SAR, structural, and physical chemical property trends. The main things needed are seen right upfront, and with the powerful ChemAxon product suite under the hood, CDD even calculates things like LogD, pka, and complex 3D simulations.
Download the full article for convenient reading below:
This blog is authored by members of the CDD Vault community. CDD Vault is a hosted drug discovery informatics platform that securely manages both private and external biological and chemical data. It provides core functionality including chemical registration, structure activity relationship, chemical inventory, and electronic lab notebook capabilities!
CDD Vault: Drug Discovery Informatics your whole project team will embrace!