Proteins, and enzymes in particular, play a pivotal role in human physiological and pathological processes. Activity-based protein profiling (ABPP) methods exploit the power of chemistry to elucidate enzyme activities and identify novel therapeutic targets.
This is a recorded webinar with respected leaders in ABPP research, professors Matt Bogyo (Stanford University) and Ben Cravatt (Scripps Research), where we delved into the science and applications of this technology for drug discovery.
Matt Bogyo is a Professor of Pathology at Stanford Medical School. His interests are focused on the use of chemistry to study the role of proteases in human disease, in particular in tumorgenesis and the life cycle of pathogens.
Prior to that, Dr. Bogyo held positions at the Department of Biochemistry and Biophysics at the University of California, San Francisco, as well as at Celera Genomics.
Dr. Bogyo received a B.Sc. degree in Chemistry from Bates College and a Ph.D. in Biochemistry from the Massachusetts Institute of Technology.
Ben Cravatt is the Gilula Chair of Chemical Biology and Professor in the Department of Chemistry at The Scripps Research Institute. His research group develops and applies chemical proteomic technologies for protein and drug discovery on a global scale and has particular interest in studying biochemical pathways in the nervous system and cancer. Dr. Cravatt is also a co-founder of several biotechnology companies.
Dr. Cravatt obtained his undergraduate education at Stanford University, receiving a B.S. in the Biological Sciences and a B.A. in History. He received his Ph.D. from Scripps Research